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A PROTEIN HELPS FIGHT DISEASES METABOLIC

is a protein called Reverb, to coordinate the body's energy level in the timeframe of 24 hours. It acts on the circulation allowing oxygen to maintain a proper metabolism. The discovery of Reverb, anticipated by Science Express, was made by a group of researchers at the University of Pennsylvania, who conducted a study funded by the National Institute of Diabetes and Digestive and Kidney Disease, with the aim to find relations between the 'clock inside the human body and certain metabolic disorders such as obesity and diabetes. "Proteins such as Reverb - say the authors of the research - make up the human clock gears and understand the role they play is important to combat metabolic diseases." Specifically, the act regulating the activity of reverb can lead to reduction in the amount of glucose produced by liver cells. According to Lazard Mitchell, director of the American Metabolic Diseases of the University, "has opened the way for a new generation of therapies for diabetes."

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Protect them with the "NEONATAL METABOLIC SCREENING BROADER "

E 'this the slogan of the national awareness campaign promoted by AISMME Onlus to extend the neonatal prevention. The "expanded metabolic newborn screening is that if a particular test run for children in the first hours of life can be identified early on until about 40 genetic diseases, metabolic diseases involving the body's biochemistry. If identified early hours of the child's life, prior to the dell'istaurarsi of irreversible damage, these conditions may be treated to ensure, if not cure, at least a satisfactory quality of life. Currently, only the region of Tuscany to practice law the "screening extended" to all newborns. AISMME non-profit organization is working for the test to be applied in all the Italian Regions by saving so many little lives and preserving them from serious psychological and physical damage. Every year in Italy, 600,000 children are born. Today with the "expanded metabolic newborn screening" a sick child is diagnosed every 1,850. For more information on the "expanded metabolic newborn screening," write to info@aismme.org

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FDA says testing on


The Food and Drug Administration (FDA) has awarded PTC Therapeutics funding amounted to $ 1.6 million to continue the trial in progress Ataluren, experimental drug to treat Duchenne dystrophy. The Phase IIb clinical trial was conducted on 174 patients in 37 centers in 11 countries worldwide, including USA, Canada, Australia and Israel. For several years, PTC Therapeutics, a note of Parent Project, a project born in Italy in 1996 to defeat the Duchenne muscular dystrophy and Becker - has developed this new type of experimental drug that works by allowing the cell to ignore the stop sign in genome and to pursue the correct coding of the dystrophin gene. The premature stop codon in the dystrophin gene is present in approximately 13% of patients with the disease. Primary endpoint of the international clinical trial is to evaluate the effectiveness of the drug on the ability to walking. Data processing with the final clinical results is scheduled for summer 2010.

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Families with Duchenne Syndrome Shox write me?

Hello, anyone of you knows a rare disease caused dall'alterazion Gene Shox? It's called discondrosteosi. Can be diagnosed through genetic testing. There are only two centers of excellence for the treatment of the syndrome gene Shox, in Emilia Romagna and Chieti. The Italians are a few hundred children. Not familiar with the number so far because the disease had no cure and once the centers of the small track was lost. Now there is hope for a therapy that prevents the eggs dysmorphism, deformities. In short, it's worth I groped. You make me know please if someone is in contact with these people? Thanks Margaret

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Program for Health Research 2008: Research on Rare Diseases

Funding for research projects are aimed at institutional recipients (DI) of the Ministry of Labour, Health and Welfare, the former paragraph 6 of art. 12/bis of Legislative Decree no. 502/92 as amended and supplemented by Legislative Decree no. 229/99, henceforth referred to as institutional recipients (DI), namely: Regions and Autonomous Provinces, National Institute of Health, National Institute Prevention and Safety, National Agency for Regional Health Services, Institute for Hospitalization and Care Scientific public and private institutions Experimental Zooprophylactic.

Limited for research projects area B are eligible for funding related to those facilities or public or private non-profit indicated in particular for the Decree Law Converted into law 269 of 30/9/2003, 24/11/2003 Act No. 236 Article 48 paragraph 19 b) and Article 1, paragraph 2, letter a) of the DM 17/12/2004, "Requirements and conditions of a general nature concerning the conduct of clinical trials of medicines, with particular reference to those for the improvement of clinical practice as an integral part of health care. " Specifically with respect to "institutional recipients' currently indicated, may compete without restriction all institutions public (including universities) and associations / foundations / societies (including patient groups) not for profit.

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Melanoma: part of the draft Myskincheck

are diagnosed each year worldwide more than 2 million cases of melanoma and the number is steadily increasing (Source: WHO). In Italy the incidence is higher than the 12-13 cases per year per 100 thousand inhabitants. Predominantly affects people in the age group between 30 and 60, with a peak around 40-50. If diagnosed in time 90% of skin cancers could be cured. Prevention is fundamental and therefore becomes a priority. For this reason La Roche-Posay and ADOI (Association of Dermatologists Italian Hospital) conducted the campaign myskincheck, a project of public health dermatology, with the aim of raising awareness to the prevention of melanoma. Accompanied by an information campaign in the free screening for prevention education, not only during the summer months but also during the year. The project, which starts in May, is divided into three specific initiatives and complementary: the www.myskincheck.it website, where you can find useful advice for their health, insights on the theme of melanoma and tools to prepare for the visit to the dermatologist and the myskincheck tour with free tours at the most important Italian beaches during the months of June and July; and the involvement of hospitals that disclose in their waiting rooms the importance of prevention of melanoma through educational videos. Italy 2007 Ipsos data show that Italians do not even take a proper behavior in the sun, 61.1% of Italians sheet and 31.4% said they had never used a sunscreen. Among those, rather than protect themselves with sunscreen, 42% do so only for the first few days of sun exposure and then abandoning the important use. Security is crucial not only during the summer holidays, but also to return to the city and on all occasions of exposure to ultraviolet light. Unfortunately, this behavior appears to be rare among healthy Italians. Only 3.4%, in fact, it is protected in the mountains in winter and 2.8% during sports or outdoor activities last year.
Melanoma is an aggressive tumor of the skin that may occur on all areas of the body where melanocytes are present, then the skin, but mucous membranes, the meninges and the eye. It looks like a stain often asymmetrical with irregular edges, very dark and with a variable magnitude. "Everyone can develop melanoma, but there are factors that can increase the risk of an outbreak. Among these surely the presence of a familial predisposition (this is approximately 10% of cases of melanoma), the presence of a phenotype with very light complexion, with blonde hair / blue eyes and red / green, the presence of more than 50 nevi and congenital nevi. The percentage of occurrence of a melanoma in a preexisting mole ranges from 20 to 80%, "says Dr. Gian Marco Tomassini, national coordinator of the group ADOI melanoma.